Associate Prof. Sheng Tang’s research group made an important progress on in-situ analytical approach for determination of H2S.
Release Time: 2019-05-10 Times for browsing: 1998

Title: Smartphone Nanocolorimetric Determination of Hydrogen Sulfide in Biosamples after Silver-Gold Core-Shell Nanoprism-Based Headspace Single-Drop Microextraction

 

Recently, a new approach to detect hydrogen sulfide (H2S) in biosamples by smartphone nanocolorimetric platform [1] was published on Analytical Chemistry by Associate Prof. Sheng Tang’s research group from School of Environmental and Chemical Engineering.

In this work, the sensitive detection of H2S was realized at low cost and high efficiency through the application of silver-gold core-shell nanoprism (Ag@Au-np) combined with headspace single-drop microextraction (HS-SDME). After SDME, smartphone nanocolorimetry (SNC), with the aid of smartphone camera and color picker software, was used to detect and quantify the H2S. The method took advantage of the inhibition of the UV-vis signal caused by H2S etching of the Ag@Au-np pre-added to the SDME solvent to measure the H2S concentration. The coating of the gold layer not only ensured the high stability of the nanomaterial but also enhanced the selectivity toward H2S. The HS-SDME method was simple to process and required only a droplet of solvent for analysis to be realized. This HS-SDME-SCN approach exhibited a calibration graph linearity of between 0.1 and 100 μM and a limit of detection of 65 nM (relative standard deviations of N% (n = 3) < 4.80). The assay demonstrated a good applicability to genuine opaque and inhomogeneous biosamples(egg and milk).

 

[1] Sheng Tang*, Tong Qi, Dasha Xia, Mengchan Xu, Mengyuan Xu, Anni Zhu, Wei Shen, and Hian Kee Lee*, Smartphone Nanocolorimetric Determination of Hydrogen Sulfide in Biosamples after Silver-Gold Core-Shell Nanoprism-Based Headspace Single-Drop Microextraction,Anal. Chem.2019, 91, 5888-5895. DOI: 10.1021/acs.analchem.9b00255.